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Article

Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity.

Journal of thrombosis and haemostasis : JTH - 1 Oct 2018

Olsson M, Stanne T M, Pedersen A, Lorentzen E, Kara E, Martinez-Palacian A, Rønnow Sand N P, Jacobsen A F, Sandset P M, Sidelmann J J, Engström G, Melander O, Kanse S M, Jern C

Abstract excerpt

Essentials Knowledge of genetic regulators of plasma factor VII activating protease (FSAP) levels is limited. We performed a genome-wide analysis of variants influencing FSAP activity in Scandinavian cohorts. We replicated an association for Marburg-1 and identified an association for a HABP2 stop variant. We identified a novel locus near ADCY2 as a potential additional regulator of FSAP activity. SUMMARY:...

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Source

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Identifiers

PMID: 30070759
DOI: 10.1111/jth.14258
PMCID: PMC6485504

Genes

HABP2
ADCY2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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