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Article

Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study.

Blood - 2 Dec 2010

Tang Weihong, Basu Saonli, Kong Xiaoxiao, Pankow James S, Aleksic Nena, Tan Adrian, Cushman Mary, Boerwinkle Eric, Folsom Aaron R

Abstract excerpt

Protein C is an important endogenous anticoagulant in hemostasis. Deficiencies of protein C due to genetic mutations or a low level of circulating protein C increase the risk of venous thromboembolism. We performed a genome-wide association scan for plasma protein C antigen concentration with approximately 2.5 million single-nucleotide polymorphisms in 8048 individuals of European ancestry and a replication...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20802025
DOI: 10.1182/blood-2010-05-283739
PMCID: PMC3012596

Genes

EDEM2
GCKR
PROC
PROCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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