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Article

Fine mapping of quantitative trait nucleotides underlying thrombin-activatable fibrinolysis inhibitor antigen levels by a transethnic study.

Blood - 1 Sept 2006

Frère Corinne, Tregouet David-Alexandre, Morange Pierre-Emmanuel, Saut Noémie, Kouassi Dinar, Juhan-Vague Irène, Tiret Laurence, Alessi Marie-Christine

Abstract excerpt

Recent studies revisiting the association between plasma thrombin-activatable fibrinolysis inhibitor (TAFI) Ag levels and polymorphisms of the CPB2 gene (coding for TAFI) suggested that TAFI Ag levels were influenced by 2 major quantitative trait nucleotides (QTNs) in European whites. However, the strong linkage disequilibrium (LD) between CPB2 polymorphisms in European whites did not allow one to distinguish...

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Identifiers

PMID: 16705091
DOI: 10.1182/blood-2006-01-008094

Genes

CPB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fine mapping of quantitative trait nucleotides underlying thrombin-activatable fibrinolysis inhibitor antigen levels by a transethnic study.PMID 16705091Read ↗

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor.Semantic proximity Read ↗

Effect of single nucleotide polymorphisms on expression of the gene encoding thrombin-activatable fibrinolysis inhibitor: a functional analysis.Semantic proximity Read ↗

A genome-wide exploration suggests an oligogenic model of inheritance for the TAFI activity and its antigen levels.Semantic proximity Read ↗

Polymorphisms in the CPB2 gene are maintained by balancing selection and result in haplotype-preferential splicing of exon 7.Semantic proximity Read ↗

A locus on chromosome 13 influences levels of TAFI antigen in healthy Mexican Americans.Semantic proximity Read ↗

Association of a single nucleotide polymorphism in CPB2 encoding the thrombin-activable fibrinolysis inhibitor (TAF1) with blood pressure.Semantic proximity Read ↗

Thrombin activatable fibrinolysis inhibitor gene polymorphisms are associated with antigenic levels in the Asian-Indian population but may not be a risk for stroke.Semantic proximity Read ↗

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Combined segregation-linkage analysis of plasma thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms.Semantic proximity Read ↗

The impact of single nucleotide polymorphisms of the thrombin activatable fibrinolysis inhibitor (TAFI) gene on TAFI antigen levels in healthy children and pediatric oncology patients.Semantic proximity Read ↗

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