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Article

A locus on chromosome 13 influences levels of TAFI antigen in healthy Mexican Americans.

Human biology - 1 Jun 2006

Warren D M, Cole S A, Dyer T D, Soria J M, Souto J C, Fontcuberta J, Blangero J, Maccluer J W, Almasy L

Abstract excerpt

When activated, thrombin activatable fibrinolysis inhibitor (TAFI) inhibits fibrinolysis by modifying fibrin, depressing its plasminogen binding potential. Polymorphisms in the TAFI structural gene (CPB2) have been associated with variation in TAFI levels, but the potential occurrence of influential quantitative trait loci (QTLs) located elsewhere in the genome has been explored only in families ascertained in...

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Source

Identifiers

PMID: 17216805
DOI: 10.1353/hub.2006.0049

Genes

CPB2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A locus on chromosome 13 influences levels of TAFI antigen in healthy Mexican Americans.PMID 17216805Read ↗

A genome-wide exploration suggests an oligogenic model of inheritance for the TAFI activity and its antigen levels.Semantic proximity Read ↗

A Genome-wide Study of Common and Rare Genetic Variants Associated with Circulating Thrombin Activatable Fibrinolysis Inhibitor.Semantic proximity Read ↗

Identification of polymorphisms in the promoter and the 3' region of the TAFI gene: evidence that plasma TAFI antigen levels are strongly genetically controlled.Semantic proximity Read ↗

Combined segregation-linkage analysis of plasma thrombin activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms.Semantic proximity Read ↗

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Effect of single nucleotide polymorphisms on expression of the gene encoding thrombin-activatable fibrinolysis inhibitor: a functional analysis.Semantic proximity Read ↗

Fine mapping of quantitative trait nucleotides underlying thrombin-activatable fibrinolysis inhibitor antigen levels by a transethnic study.Semantic proximity Read ↗

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