Article
After 18 months of antiretroviral therapy, total HIV DNA decreases more pronouncedly in patients infected by CRF01_AE than in those infected by subtype B and CRF07_BC.
Microbiology and immunology - 1 Apr 2018
Lu Zhenzhen, Jiao Yanmei, Li Jianjun, Lan Guanghua, Lu Chunyan, Li Xuan, Tang Zhenzhu, Wang Ning
Abstract excerpt
Whether the amount of HIV DNA is associated with the subtype of HIV-1 after antiretroviral therapy (ART) has not been reported. In the present study, the amount of HIV DNA and RNA and CD4+T counts in blood and semen prior to and after 18 months of ART were compared in 48 patients infected by CRF01_AE, subtype B or CRF07_BC of HIV-1. Viral RNA was suppressed and CD4 cell count recovery achieved in all patients....
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