Article
Predominance of CXCR4 tropism in HIV-1 CRF14_BG strains from newly diagnosed infections.
The Journal of antimicrobial chemotherapy - 1 Jan 2014
Pérez-Álvarez Lucía, Delgado Elena, Vega Yolanda, Montero Vanessa, Cuevas Teresa, Fernández-García Aurora, García-Riart Beatriz, Pérez-Castro Sonia, Rodríguez-Real Ricardo, López-Álvarez María José, Fernández-Rodríguez Ricardo, Lezaun María Jesús, Ordóñez Patricia, Ramos Carmen, Bereciartua Elena, Calleja Sara, Sánchez-García Ana M, Thomson Michael M
Abstract excerpt
OBJECTIVES: R5-tropic viruses are associated with HIV-1 transmission and predominate during the early stages of infection. X4-tropic populations have been detected in ~50% of patients with late-stage disease infected with subtype B viruses. In this study, we compared the frequency of X4 tropism in individuals infected with HIV-1 CRF14_BG viruses, which have a V3 loop of subtype B, with a control group of...
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