Article
Structural equation modelling of viral tropism reveals its impact on achieving viral suppression within 6 months in treatment-naive HIV-1-infected patients after combination antiretroviral therapy.
The Journal of antimicrobial chemotherapy - 1 Jan 2017
Mengoli Carlo, Andreis Samantha, Scaggiante Renzo, Cruciani Mario, Bosco Oliviero, Ferretto Roberto, Leoni Davide, Maffongelli Gaetano, Basso Monica, Torti Carlo, Sarmati Loredana, Andreoni Massimo, Palù Giorgio, Parisi Saverio Giuseppe
Abstract excerpt
OBJECTIVES: To evaluate the role of pre-treatment co-receptor tropism of plasma HIV on the achievement of viral suppression (plasma HIV RNA 1.69 log10 copies/mL) at the sixth month of combination antiretroviral therapy (cART) in a cohort of naive patients using, for the first time in this context, a path analysis (PA) approach. PATIENTS AND METHODS: Adult patients with chronic infection by subtype B HIV-1 were...
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