Article
High prevalence of CXCR4 usage among treatment-naive CRF01_AE and CRF51_01B-infected HIV-1 subjects in Singapore.
BMC infectious diseases - 19 Feb 2013
Ng Kah Ying, Chew Kuan Kiat, Kaur Palvinder, Kwan Joe Yap, Khong Wei Xin, Lin Li, Chua Arlene, Tan Mei Ting, Quinn Thomas C, Laeyendecker Oliver, Leo Yee Sin, Ng Oon Tek
Abstract excerpt
BACKGROUND: Recent studies suggest HIV-1 inter-subtype differences in co-receptor usage. We examined the correlation between HIV-1 subtype and co-receptor usage among treatment-naïve HIV-1 subjects in Singapore. Additionally, we investigated whether the subtype co-receptor association was influenced by stage of infection. METHODS: V3 sequences of HIV-1 envelope protein gp120 were obtained from 110 HIV...
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