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Article

Low frequency of CXCR4-using viruses in patients at the time of primary non-subtype-B HIV-1 infection.

Journal of clinical microbiology - 1 Oct 2010

Frange Pierre, Chaix Marie-Laure, Raymond Stéphanie, Galimand Julie, Deveau Christiane, Meyer Laurence, Goujard Cécile, Rouzioux Christine, Izopet Jacques

Abstract excerpt

We used genotypic and phenotypic assays to estimate the frequency of X4/DM viruses in 131 patients infected with non-subtype-B viruses at the time of primary HIV-1 infection (PHI). All patients were enrolled in the French PRIMO Cohort from 1996 to 2007. Most strains belonged to CRF02_AG (51.1%) and subtype A (14.5%). Sixteen viruses (12.2%) were classified as CXCR4 tropic ("X4 strains") by the combined criteria...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20686090
DOI: 10.1128/JCM.00704-10
PMCID: PMC2953081

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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