Increasing HIV-1 non-B subtype primary infections in patients in France and effect of HIV subtypes on virological and immunological responses to combined antiretroviral therapy.

doi:10.1093/cid/cis999

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Increasing HIV-1 non-B subtype primary infections in patients in France and effect of HIV subtypes on virological and immunological responses to combined antiretroviral therapy.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Mar 2013

Chaix Marie-Laure, Seng Remonie, Frange Pierre, Tran Laurent, Avettand-Fenoël Véronique, Ghosn Jade, Reynes Jacques, Yazdanpanah Yazdan, Raffi François, Goujard Cécile, Rouzioux Christine, Meyer Laurence

Abstract excerpt

BACKGROUND: To analyze the time trends of the viral subtype distributions according to gender, risk group, and geographical origin of the patients in 1128 primary human immunodeficiency virus type 1 infection (PHI), diagnosed in France (1996-2010). To study whether the viral diversity had an impact on the virological and immunological responses in patients initiating combined antiretroviral therapy (cART) soon...

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PMID: 23223603
DOI: 10.1093/cid/cis999

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