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CRF01_AE and CRF01_AE Cluster 4 Are Associated With Poor Immune Recovery in Chinese Patients Under Combination Antiretroviral Therapy.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 18 May 2021

Ge Zhangwen, Feng Yi, Li Kang, Lv Bowen, Zaongo Silvere D, Sun Jia, Liang Yanling, Liu Dan, Xing Hui, Wei Min, Ma Ping, Shao Yiming

Abstract excerpt

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) clades and clusters have different epidemic patterns and phenotypic profiles. It is unclear if they also affect patients' immune recovery (IR) in combination antiretroviral therapy (cART). METHODS: We conducted a cohort study on 853 patients under cART for evaluating the impacts of viral factor on host IR. We used generalized estimating equations for factors...

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PMID: 32296820
DOI: 10.1093/cid/ciaa380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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