Article
Immune reconstruction effectiveness of combination antiretroviral therapy for HIV-1 CRF01_AE cluster 1 and 2 infected individuals.
Emerging microbes & infections - 1 Dec 2022
Li Kang, Chen Huanhuan, Li Jianjun, Feng Yi, Lan Guanghua, Liang Shujia, Liu Meiliang, Rashid Abdur, Xing Hui, Shen Zhiyong, Shao Yiming
Abstract excerpt
There are great disparities of the results in immune reconstruction (IR) of the HIV-1 infected patients during combined antiretroviral therapy (cART), due to both host polymorphisms and viral genetic subtypes. Identifying these factors and elucidating their impact on the IR could help to improve the efficacy. To study the factors influencing the IR, we conducted a 15-year retrospective cohort study of HIV-1...
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