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Article

Leptin receptor q223r polymorphism influences neutrophil mobilization after Clostridium difficile infection.

Mucosal immunology - 1 May 2018

Jose S, Abhyankar M M, Mukherjee A, Xue J, Andersen H, Haslam D B, Madan R

Abstract excerpt

Clostridium difficile is the leading cause of nosocomial infections in the United States. Clinical disease outcomes after C. difficile infection (CDI) are dependent on intensity of host inflammatory responses. Specifically, peak peripheral white blood cell (WBC) count >20 × 109 l-1 is an indicator of adverse outcomes in CDI patients, and is associated with higher 30-day mortality. We show that homozygosity for a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 29363668
DOI: 10.1038/mi.2017.119
PMCID: PMC5976520

Genes

CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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