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Article

IL-10 and IL-10 receptor defects in humans.

Annals of the New York Academy of Sciences - 1 Dec 2011

Glocker Erik-Oliver, Kotlarz Daniel, Klein Christoph, Shah Neil, Grimbacher Bodo

Abstract excerpt

Inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), is chronic in nature and is characterized by abdominal pain, diarrhea, bleeding, and malabsorption. It is considered a complex multigenic and multifactorial disorder that results from disturbed interactions between the immune system and commensal bacteria of the gut. Recent work has demonstrated that IBD with an...

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Identifiers

PMID: 22236434
DOI: 10.1111/j.1749-6632.2011.06339.x

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