Article
The presence of IL-8 +781 T/C polymorphism is associated with the parameters of severe Clostridium difficile infection.
Microbial pathogenesis - 1 Jan 2018
Czepiel Jacek, Biesiada Grażyna, Dróżdż Mirosław, Gdula-Argasińska Joanna, Żurańska Justyna, Marchewka Jakub, Perucki William, Wołkow Paweł, Garlicki Aleksander
Abstract excerpt
PURPOSE: There is large variation in the clinical manifestations of Clostridium difficile infection (CDI). We also still can not predict which patients are more susceptible to reinfection with CDI. The aim of our study was to evaluate the effect of gene single nucleotide polymorphisms (SNP) of proinflammatory cytokines, specifically IL-1β, IL-8 on the development, clinical course and recurrence of CDI. METHODS:...
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