Article
High Resolution Melting Analysis for Rapid Detection of PIK3CA Gene Mutations in Bladder Cancer: A Mutated Target for Cancer Therapy.
Urology journal - 23 Jan 2018
Ousati Ashtiani Zahra, Mehrsai Abdol Rasoul, Pourmand Mohammad Reza, Pourmand Gholam Reza
Abstract excerpt
PURPOSE: PIK3CA gene mutations have clinical importance and their presence is associated with therapy response. They are also considered as a molecule for targeted therapy. As regards to their importance, genetic variation within a population as well as among different populations, this study was conducted to detect common mutations of exons 9 and 20 and other probable mutations in PIK3CA gene as well as their...
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