Article
Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population.
Clinica chimica acta; international journal of clinical chemistry - 9 Oct 2012
Hsieh Li-Ling, Er Tze-Kiong, Chen Chih-Chieh, Hsieh Jan-Sing, Chang Jan-Gowth, Liu Ta-Chih
Abstract excerpt
BACKGROUND: The identification of KRAS, BRAF, and PIK3CA mutations before the administration of anti-epidermal growth factor receptor therapy of colorectal cancer has become important. The aim of the present study was to investigate the occurrence of KRAS, BRAF, and PIK3CA mutations in the Taiwanese population with colorectal cancer. This study was undertaken to identify BRAF and PIK3CA mutations in patients with...
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