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Article

Detection of oncogenic mutations in cervical carcinoma using method High Resolution Melting (HRM).

Neoplasma - 1 Jan 2016

Wayhelova M, Mikulasova A, Smetana J, Vallova V, Blazkova D, Filkova H, Moukova L, Kuglik P

Abstract excerpt

Oncogenic mutations in proto-oncogenes and tumor suppressor genes represent one of key events in cancerogenesis. In this study, we analysed mutation status in PIK3CA, KRAS and EGFR proto-oncogenes and TP53 tumor suppressor gene in a cohort of twenty-four patients diagnosed with squamous cell carcinoma or adenocarcinoma using the screening method "High Resolution Melting" (HRM). Positive findings were confirmed...

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Share to Carcinogenesis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Class I Phosphatidylinositol 3-Kinases

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Share to Proto-Oncogene Proteins p21(ras)

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Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 27468883
DOI: 10.4149/neo_2016_516

Genes

KRAS
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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