Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathway Analysis of Genome-wide Association Study in Childhood Leukemia among Hispanics.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2016

Hsu Ling-I, Briggs Farren, Shao Xiaorong, Metayer Catherine, Wiemels Joseph L, Chokkalingam Anand P, Barcellos Lisa F

Abstract excerpt

BACKGROUND: The incidence of acute lymphoblastic leukemia (ALL) is nearly 20% higher among Hispanics than non-Hispanic Whites. Previous studies have shown evidence for association between risk of ALL and variation within IKZF1, ARID5B, CEBPE, CDKN2A, GATA3, and BM1-PIP4K2A genes. However, variants identified only account for <10% of the genetic risk of ALL. METHODS: We applied pathway-based analyses to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to GATA3 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to IKZF1 gene

Share to IMPACT gene

Share to Genome-Wide Association Study

Share to Genotype

Share to Hispanic or Latino

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Open in PubMed Open full text

Identifiers

PMID: 26941364
DOI: 10.1158/1055-9965.EPI-15-0528
PMCID: PMC4873450

Genes

GATA3
IKZF1
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathway Analysis of Genome-wide Association Study in Childhood Leukemia among Hispanics.PMID 26941364Read ↗

GWAS in childhood acute lymphoblastic leukemia reveals novel genetic associations at chromosomes 17q12 and 8q24.21.Semantic proximity Read ↗

Novel Gene and Network Associations Found for Acute Lymphoblastic Leukemia Using Case-Control and Family-Based Studies in Multiethnic Populations.Semantic proximity Read ↗

Family-based exome-wide association study of childhood acute lymphoblastic leukemia among Hispanics confirms role of ARID5B in susceptibility.Semantic proximity Read ↗

Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci.Semantic proximity Read ↗

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.Semantic proximity Read ↗

Investigating DNA methylation as a mediator of genetic risk in childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Genetic susceptibility in childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Transcriptome Analysis in Mexican Adults with Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Genetic defects in hematopoietic transcription factors and predisposition to acute lymphoblastic leukemiaSemantic proximity Read ↗

Genetic variants in ARID5B and CEBPE are childhood ALL susceptibility loci in Hispanics.Semantic proximity Read ↗

ARID5B, CEBPE and PIP4K2A Germline Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in Mexican Patients: A MIGICCL Study.Semantic proximity Read ↗

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.