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Faster progression from MCI to probable AD for carriers of a single-nucleotide polymorphism associated with type 2 diabetes.

Neurobiology of aging - 1 Apr 2018

Girard Hugo, Potvin Olivier, Nugent Scott, Dallaire-Théroux Caroline, Cunnane Stephen, Duchesne Simon

Abstract excerpt

Sporadic Alzheimer's disease (AD), as opposed to its autosomal dominant form, is likely caused by a complex interaction of genetic, environmental, and health lifestyle factors. Twin studies indicate that sporadic AD heritability could be between 58% and 79%, around half of which is explained by the ε4 allele of the apolipoprotein E (APOE4). We hypothesized that genes associated with known risk factors for AD,...

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PMID: 29338921
DOI: 10.1016/j.neurobiolaging.2017.11.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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