Article

Evaluating the causal association between type 2 diabetes and Alzheimer's disease: a Two-Sample Mendelian Randomisation Study

2024-12-20

Abstract excerpt

<h4>Aims: </h4> Type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) are significant global health issues. Epidemiological studies suggest T2DM increases AD risk, though confounding factors and reverse causality complicate this association. This study aims to clarify the causal relationship between T2DM and AD through a systematic review and meta-analysis of Mendelian randomization (MR) studies and a new t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 53c05865-12ff-52c9-b4a6-a22972b3b467
DOI: 10.1101/2024.12.19.24319309

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evaluating the causal association between type 2 diabetes and Alzheimer's disease: a Two-Sample Mendelian Randomisation StudyDOI 10.1101/2024.12.19.24319309Read

Evaluating the Causal Association Between Type 2 Diabetes and Alzheimer’s Disease: A Two-Sample Mendelian Randomization StudySemantic proximity Read

Evaluating the Causal Effect of Type 2 Diabetes on Alzheimer's Disease Using Large-Scale Genetic Data.Semantic proximity Read

Causal relationships between type 1 diabetes mellitus and Alzheimer's disease and Parkinson's disease: a bidirectional two-sample Mendelian randomization study.Semantic proximity Read

Type-2 diabetes and risk of dementia: observational and Mendelian randomisation studies in 1 million individuals.Semantic proximity Read

Causal Effects of Type 2 Diabetes and Glycemic Traits on Dementia and Stroke: A Mendelian Randomization Study including Imaging EndpointsSemantic proximity Read

Systematic evaluation of multifactorial causal associations for Alzheimer's disease and an interactive platform based on Mendelian randomization analysis——MRADSemantic proximity Read

Linking Parkinson’s disease and Alzheimer’s disease: A Mendelian Randomization Study on Causal Relationships and Clinical ImplicationsSemantic proximity Read

Five Major Psychiatric Disorders and Alzheimer's Disease: A Bidirectional Mendelian Randomization Study.Semantic proximity Read

Causal Relationship between Inflammatory Proteins and Alzheimer's Disease: A Two-Sample Bidirectional Mendelian Randomization Study.Semantic proximity Read

Unraveling the link: exploring the causal relationship between diabetes, multiple sclerosis, migraine, and Alzheimer’s disease through Mendelian randomizationSemantic proximity Read

Mendelian randomization study of diabetes and dementia in the Million Veteran ProgramSemantic proximity Read

Glycemic traits and Alzheimer's disease: a Mendelian randomization study.Semantic proximity Read