Article
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Archives of neurology - 1 Jan 2008
Li Hao, Wetten Sally, Li Li, St Jean Pamela L, Upmanyu Ruchi, Surh Linda, Hosford David, Barnes Michael R, Briley James David, Borrie Michael, Coletta Natalie, Delisle Richard, Dhalla Daniella, Ehm Margaret G, Feldman Howard H, Fornazzari Luis, Gauthier Serge, Goodgame Neil, Guzman Danilo, Hammond Sandra, Hollingworth Paul, Hsiung Ging-Yuek, Johnson Joan, Kelly Devon D, Keren Ron, Kertesz Andrew, King Karen S, Lovestone Simon, Loy-English Inge, Matthews Paul M, Owen Michael J, Plumpton Mary, Pryse-Phillips William, Prinjha Rab K, Richardson Jill C, Saunders Ann, Slater Andrew J, St George-Hyslop Peter H, Stinnett Sandra W, Swartz Jina E, Taylor Rachel L, Wherrett John, Williams Julie, Yarnall David P, Gibson Rachel A, Irizarry Michael C, Middleton Lefkos T, Roses Allen D
Abstract excerpt
OBJECTIVE: To identify single-nucleotide polymorphisms (SNPs) associated with risk and age at onset of Alzheimer disease (AD) in a genomewide association study of 469 438 SNPs. DESIGN: Case-control study with replication. SETTING: Memory referral clinics in Canada and the United Kingdom. PARTICIPANTS: The hypothesis-generating data set consisted of 753 individuals with AD by National Institute of Neurological and...
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