Article
CDK5RAP2 gene and tau pathophysiology in late-onset sporadic Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jun 2018
Miron Justin, Picard Cynthia, Nilsson Nathalie, Frappier Josée, Dea Doris, Théroux Louise, Poirier Judes
Abstract excerpt
INTRODUCTION: Because currently known Alzheimer's disease (AD) single-nucleotide polymorphisms only account for a small fraction of the genetic variance in this disease, there is a need to identify new variants associated with AD. METHODS: Our team performed a genome-wide association study in the Quebec Founder Population isolate to identify novel protective or risk genetic factors for late-onset sporadic AD and...
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