Article
Linking Alzheimer's disease and type 2 diabetes: Novel shared susceptibility genes detected by cFDR approach.
Journal of the neurological sciences - 15 Sept 2017
Wang Xia-Fang, Lin Xu, Li Ding-You, Zhou Rou, Greenbaum Jonathan, Chen Yuan-Cheng, Zeng Chun-Ping, Peng Lin-Ping, Wu Ke-Hao, Ao Zeng-Xin, Lu Jun-Min, Guo Yan-Fang, Shen Jie, Deng Hong-Wen
Abstract excerpt
BACKGROUND: Both type 2 diabetes (T2D) and Alzheimer's disease (AD) occur commonly in the aging populations and T2D has been considered as an important risk factor for AD. The heritability of both diseases is estimated to be over 50%. However, common pleiotropic single-nucleotide polymorphisms (SNPs)/loci have not been well-defined. The aim of this study is to analyze two large public accessible GWAS datasets to...
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