Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histologic and immunohistochemical differences between hereditary and sporadic diffuse gastric carcinoma.

Human pathology - 1 Apr 2018

Lee Hee Eun, Smyrk Thomas C, Zhang Lizhi

Abstract excerpt

We aimed to identify histopathologic features unique in hereditary diffuse gastric cancer (HDGC) by comparing with its sporadic counterpart (SDGC). 11 patients with confirmed CDH1 mutation who were found to have HDGC in a prophylactic total gastrectomy were collected. Median age of HDGC patients was 39 years (range 24-57). All HDGC cases had intramucosal signet ring cell carcinoma. Twenty-three invasive tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Signet Ring Cell
Share to Gastrectomy
Share to Gastric Mucosa

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Immunohistochemistry

Share to Stomach

Share to Stomach Neoplasms

Share to Young Adult

Source

Identifiers

PMID: 29307626
DOI: 10.1016/j.humpath.2017.12.023

Genes

CDX2
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histologic and immunohistochemical differences between hereditary and sporadic diffuse gastric carcinoma.PMID 29307626Read ↗

Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future.Semantic proximity Read ↗

Pathological features of total gastrectomy specimens from asymptomatic hereditary diffuse gastric cancer patients and implications for clinical management.Semantic proximity Read ↗

Histopathologic Analysis of Signet-ring Cell Carcinoma In Situ in Patients With Hereditary Diffuse Gastric Cancer.Semantic proximity Read ↗

CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And TreatmentSemantic proximity Read ↗

Case series of three patients with hereditary diffuse gastric cancer in a single family: Three case reports and review of literature.Semantic proximity Read ↗

Diffuse gastric cancer: histologic, molecular, and genetic basis of diseaseSemantic proximity Read ↗

The Changing Landscape of Hereditary Diffuse Gastric Cancer.Semantic proximity Read ↗

Hereditary diffuse gastric cancer (HDGC). An overview.Semantic proximity Read ↗

Overview on new progress of hereditary diffuse gastric cancer with CDH1 variants.Semantic proximity Read ↗

Hereditary Diffuse Gastric Cancer.Semantic proximity Read ↗

Current advances in understanding the molecular profile of hereditary diffuse gastric cancer and its clinical implications.Semantic proximity Read ↗

Histological and mutational profile of diffuse gastric cancer: current knowledge and future challengesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.