Article
The effects of transcription and recombination on mutational dynamics of short tandem repeats.
Nucleic acids research - 16 Feb 2018
Zavodna Monika, Bagshaw Andrew, Brauning Rudiger, Gemmell Neil J
Abstract excerpt
Short tandem repeats (STR) are ubiquitous components of the genomic architecture of most living organisms. Recent work has highlighted the widespread functional significance of such repeats, particularly around gene regulation, but the mutational processes underlying the evolution of these highly abundant and highly variable sequences are not fully understood. Traditional models assume that strand misalignment...
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