Article
Probing instructions for expression regulation in gene nucleotide compositions.
PLoS computational biology - 1 Jan 2018
Bessière Chloé, Taha May, Petitprez Florent, Vandel Jimmy, Marin Jean-Michel, Bréhélin Laurent, Lèbre Sophie, Lecellier Charles-Henri
Abstract excerpt
Gene expression is orchestrated by distinct regulatory regions to ensure a wide variety of cell types and functions. A challenge is to identify which regulatory regions are active, what are their associated features and how they work together in each cell type. Several approaches have tackled this problem by modeling gene expression based on epigenetic marks, with the ultimate goal of identifying driving regions...
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