Article

Gene nucleotide composition accurately predicts expression and is linked to topological chromatin domains

2017-03-16

Abstract excerpt

Gene expression is orchestrated by distinct regulatory regions (e.g. promoters, enhancers, UTRs) to ensure a wide variety of cell types and functions. A challenge is to identify which regulatory regions are active, what are their associated features and how they work together in each cell type. Several approaches have tackled this problem by modeling gene expression based on epigenetic marks (e.g. ChIP-seq, methyl...

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Literature Corpus work: 93076024-c4b6-5b81-8276-13b82e90a5c9
DOI: 10.1101/117499

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