Article

Understanding gene regulatory mechanisms based on gene classification

2021-11-02

Abstract excerpt

The CpG dinucleotide and its methylation play vital roles in gene regulation as well as 3D genome organization. Previous studies have divided genes into several categories based on the CpG intensity around transcription starting sites (TSS) and found that housekeeping genes tend to possess high CpG density while tissue-specific genes are generally characterized by low CpG density. In this study, we investigated ho...

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Literature Corpus work: c5aee1f6-ee72-553a-8e00-79765a998cae
DOI: 10.1101/2021.10.31.466641

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