Article

Decoding transcriptional regulation via a human gene expression predictor

2020-04-08

Abstract excerpt

<h4>ABSTRACT</h4> Transcription factors (TF) regulate cellular activities via controlling gene expression, but a predictive model describing how TFs quantitatively modulate human transcriptomes was lacking. We constructed a universal human gene expression predictor and utilized it to decode transcriptional regulation. Using 1613 TFs’ expression, the predictor reconstituted highly accurate transcriptomes for sampl...

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Literature Corpus work: abd7f103-64d5-5bf2-84f5-3942e9303fba
DOI: 10.1101/2020.04.07.029470

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