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Article

Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study.

BMC cancer - 6 Apr 2023

Huang Qiang, Li Feiran, Ji Mengyou, Lin Lan, Hu Chunyan

Abstract excerpt

PURPOSE: To evaluate prognostic significance of human papillomavirus (HPV) in hypopharyngeal squamous cell carcinoma patients, and to investigate the effect of p53 and TP53 mutations on the prognosis of patients. METHODS: A total of 111 patients were enrolled in our retrospective study. HPV infection status was detected in formalin-fixed paraffin-embedded tissue by real-time multiplex PCR test. p53 expression was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37024846
DOI: 10.1186/s12885-023-10775-9
PMCID: PMC10080797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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