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Article

Healthy versus Entorhinal Cortical Atrophy Identification in Asymptomatic APOE4 Carriers at Risk for Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Konishi Kyoko, Joober Ridha, Poirier Judes, MacDonald Kathleen, Chakravarty Mallar, Patel Raihaan, Breitner John, Bohbot Véronique D

Abstract excerpt

Early detection of Alzheimer's disease (AD) has been challenging as current biomarkers are invasive and costly. Strong predictors of future AD diagnosis include lower volume of the hippocampus and entorhinal cortex, as well as the ɛ4 allele of the Apolipoprotein E gene (APOE) gene. Therefore, studying functions that are critically mediated by the hippocampus and entorhinal cortex, such as spatial memory, in APOE...

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Source

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Identifiers

PMID: 29278888
DOI: 10.3233/JAD-170540
PMCID: PMC5798531

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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