Article

Unmasking selective path integration deficits in Alzheimer’s disease risk carriers

2019-10-18

Abstract excerpt

<h4>Summary</h4> Alzheimer’s disease (AD) manifests with progressive memory loss and spatial disorientation. Neuropathological studies suggest early AD pathology in the entorhinal cortex (EC) of young adults at genetic risk for AD ( APOE ε4-carriers). Because the EC harbors grid cells, a likely neural substrate of path integration (PI), we examined PI performance in APOE ε4-carriers during a virtual navigation tas...

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Literature Corpus work: 59b53b9d-8511-5d20-8a73-fec738e8e4d3
DOI: 10.1101/19009662

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