Article
αvβ6-Fyn Kinase Promotes Epithelial Phenotype in SYF Cells.
Anticancer research - 1 Jan 2018
Lee Casey, Ramos Daniel M
Abstract excerpt
The 5-year survival rate for patients with oral cancer remains at 50%, in large part due the high rate of post-treatment recurrence. In this study, we transfected epithelial-specific integrin αvβ6 and Fyn-kinase, a member of the Src-family kinases, into embryonic murine fibroblasts. In oral cancer, expression of αvβ6 is neo-expressed. Using a variety of in vitro assays, including cell migration and multicellular...
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