Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transition

30 Jun 2021

Abstract excerpt

Over a century of scientific inquiry since the discovery of v-SRC but still no final judgement on SRC function. However, a significant body of work has defined Src family kinases as key players in tumor progression, invasion and metastasis in human cancer. With the ever-growing evidence supporting the role of epithelial-mesenchymal transition (EMT) in invasion and metastasis, so does our understanding of the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related Molecular Pathways
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34193161
DOI: 10.1186/s12964-021-00750-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transitionPMID 34193161Read ↗

Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned So FarSemantic proximity Read ↗

SRC: A Century of Science Brought to the ClinicSemantic proximity Read ↗

Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial–mesenchymal transition and colorectal cancer aggressivenessSemantic proximity Read ↗

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.Semantic proximity Read ↗

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors.Semantic proximity Read ↗

The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases.Semantic proximity Read ↗

Src Continues Aging: Current and Future Clinical DirectionsSemantic proximity Read ↗

Tks adaptor proteins at a glanceSemantic proximity Read ↗

Src Family Tyrosine Kinases in Intestinal Homeostasis, Regeneration and TumorigenesisSemantic proximity Read ↗

Activation of the actin/MRTF-A/SRF signalling pathway in pre-malignant mammary epithelial cells by P-cadherin is essential for transformationSemantic proximity Read ↗

Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturationSemantic proximity Read ↗

The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.