Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of Src family kinases in growth and migration of glioma stem cells

9 May 2014

Abstract excerpt

Src family kinases (SFKs) are highly expressed and active in clinical glioblastoma multiforme (GBM) specimens. SFKs inhibitors have been demonstrated to inhibit proliferation and migration of glioma cells. However, the role of SFKs in glioma stem cells (GSCs), which are important for treatment resistance and recurrence, has not been reported. Here, we examined the expression pattern of individual members of SFKs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Mechanisms and Therapy
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24819299
DOI: 10.3892/ijo.2014.2432

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of Src family kinases in growth and migration of glioma stem cellsPMID 24819299Read ↗

Src Family Kinases as Therapeutic Targets in Advanced Solid Tumors: What We Have Learned So FarSemantic proximity Read ↗

Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients.Semantic proximity Read ↗

FYN: emerging biological roles and potential therapeutic targets in cancerSemantic proximity Read ↗

TLK2 enhances aggressive phenotypes of glioblastoma cells through the activation of SRC signaling pathwaySemantic proximity Read ↗

Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastomaSemantic proximity Read ↗

STAT3 as a Therapeutic Target for GlioblastomaSemantic proximity Read ↗

The role of Src in solid and hematologic malignancies: development of new-generation Src inhibitors.Semantic proximity Read ↗

Dual inhibition of Src and PLK1 regulate stemness and induce apoptosis through Notch1-SOX2 signaling in EGFRvIII positive glioma stem cells (GSCs)Semantic proximity Read ↗

Sema3C Promotes the Survival and Tumorigenicity of Glioma Stem Cells through Rac1 ActivationSemantic proximity Read ↗

Comprehensive Analysis of Prognostic Value and Immune Infiltration of Src Family Kinases in Hepatocellular CarcinomaSemantic proximity Read ↗

Src family kinases, adaptor proteins and the actin cytoskeleton in epithelial-to-mesenchymal transitionSemantic proximity Read ↗

Constitutive Activation of Signal Transducer and Activator of Transcription 3 (STAT3) and Nuclear Factor κB Signaling in Glioblastoma Cancer Stem Cells Regulates the Notch PathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.