Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FYNagling divergent adhesive functions for Fyn in keratinocytes.

Experimental dermatology - 1 Feb 2015

Fenton Sarah E, Denning Mitchell F

Abstract excerpt

Fyn, a member of the Src family kinases (SFKs), has been shown to play important yet contradictory roles in keratinocyte (KC) adhesion. During KC differentiation, physiological activation of Fyn results in the formation of adherens junctions, recruiting junctional components and inducing signaling pathways that control the differentiation program. However, in KC transformation and oncogenesis, increased Fyn...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adherens Junctions
Share to Cell Adhesion
Share to Cell Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Cell Movement

Share to Gene Expression Regulation

Share to Keratinocytes

Share to Proto-Oncogene Proteins c-fyn

Source

Identifiers

PMID: 24980626
DOI: 10.1111/exd.12485

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FYNagling divergent adhesive functions for Fyn in keratinocytes.PMID 24980626Read ↗

FYN: emerging biological roles and potential therapeutic targets in cancerSemantic proximity Read ↗

Srcasm corrects Fyn-induced epidermal hyperplasia by kinase down-regulation.Semantic proximity Read ↗

Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell-cell adhesion.Semantic proximity Read ↗

Focal adhesion complex proteins in epidermis and squamous cell carcinomaSemantic proximity Read ↗

Hemidesmosomes and focal contact proteins: Functions and cross-talk in keratinocytes, bullous diseases and wound healingSemantic proximity Read ↗

RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes.Semantic proximity Read ↗

αvβ6-Fyn Kinase Promotes Epithelial Phenotype in SYF Cells.Semantic proximity Read ↗

The aspartic acid of Fyn at 390 is critical for neuronal migration during corticogenesis.Semantic proximity Read ↗

The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn.Semantic proximity Read ↗

Skin abnormality in aged fyn-/- fak+/- mice.Semantic proximity Read ↗

STAT3 deficiency in keratinocytes leads to compromised cell migration through hyperphosphorylation of p130(cas).Semantic proximity Read ↗

An Important Role for Protein Kinase C-δ in Human Keratinocyte Migration on Dermal CollagenSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.