Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of pleiotropic genetic variants affecting osteoporosis risk in a Korean elderly cohort.

Journal of bone and mineral metabolism - 1 Jan 2019

Hong Eun Pyo, Rhee Ka Hyun, Kim Dong Hyun, Park Ji Wan

Abstract excerpt

Pleiotropy has important implications for understanding the genetic basis and risk assessment of osteoporosis. Our aim was to identify pleiotropic genetic variants associated with the development of osteoporosis and predict osteoporosis risk by leveraging pleiotropic variants. We evaluated the effects of 21 conventional risk factors and 185 single-nucleotide polymorphisms (SNPs) in 63 inflammation- and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Ontology
Share to Gene Regulatory Networks
Share to Genetic Pleiotropy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Incidence

Share to Inflammation

Share to Kaplan-Meier Estimate

Share to Osteoporosis

Share to Republic of Korea

Source

Identifiers

PMID: 29273888
DOI: 10.1007/s00774-017-0892-x

Genes

PPARG
EPHA7
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of pleiotropic genetic variants affecting osteoporosis risk in a Korean elderly cohort.PMID 29273888Read ↗

Bivariate genome-wide association analysis identified three pleiotropic loci underlying osteoporosis and obesity.Semantic proximity Read ↗

Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method.Semantic proximity Read ↗

Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.Semantic proximity Read ↗

Osteoporosis: A Silent Disease with Complex Genetic Contribution.Semantic proximity Read ↗

Identifying potentially common genes between dyslipidemia and osteoporosis using novel analytical approaches.Semantic proximity Read ↗

Understanding the complex genetic architecture connecting rheumatoid arthritis, osteoporosis and inflammation: discovering causal pathways.Semantic proximity Read ↗

Gene variants for osteoporosis and their pleiotropic effects in aging.Semantic proximity Read ↗

Association between polymorphisms of glucagon-like peptide-1 receptor gene and susceptibility to osteoporosis in Chinese postmenopausal women.Semantic proximity Read ↗

Genetic epidemiology of age-related osteoporosis and its clinical applications.Semantic proximity Read ↗

Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis.Semantic proximity Read ↗

Genetic Pleiotropy of Bone-Related Phenotypes: Insights from Osteoporosis.Semantic proximity Read ↗

Identification of novel variants associated with osteoporosis, type 2 diabetes and potentially pleiotropic loci using pleiotropic cFDR method.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.