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Article

Association between polymorphisms of glucagon-like peptide-1 receptor gene and susceptibility to osteoporosis in Chinese postmenopausal women.

Journal of orthopaedic surgery and research - 23 Dec 2024

Bao Xiaoxue, Liu Chang, Liu Huiming, Wang Yan, Xue Peng, Li Yukun

Abstract excerpt

BACKGROUND: The influence of the glucagon-like peptide-1 receptor (GLP-1R) on bone metabolism is well-established. However, it has been observed that single nucleotide polymorphisms (SNPs) in the GLP-1R gene can partially affect its function. Therefore, this study aims to investigate the association between SNPs in the GLP-1R gene and postmenopausal osteoporosis (PMOP) within the Chinese Han population. METHODS:...

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Identifiers

PMID: 39716293
DOI: 10.1186/s13018-024-05361-z
PMCID: PMC11667832

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