Gene variants for osteoporosis and their pleiotropic effects in aging.

doi:10.1016/j.mam.2005.01.002

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Article

Gene variants for osteoporosis and their pleiotropic effects in aging.

Molecular aspects of medicine - 1 Jun 2005

Ferrari Serge L, Rizzoli R

Abstract excerpt

The prevalence of osteoporosis is raising worldwide as improving conditions of living and treatment of other common diseases continuously increases life expectancy. Thus, osteoporosis affects most women above 80 years of age and, at the age of 50, the lifetime risk of suffering an osteoporosis-related fracture approaches 50% in women and 20% in men. Numerous genetic, hormonal, nutritional and life-style factors...

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Topics

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Share to Aging
Share to ESR1 gene
Share to LRP5 gene
Share to Genetic Variation
Share to Interleukin-6
Share to Osteoporosis
Share to Receptors, Cell Surface
Share to Receptors, Cytoplasmic and Nuclear

Source

Open in PubMed

Identifiers

PMID: 15811432
DOI: 10.1016/j.mam.2005.01.002

Genes

VDR
ESR1
LRP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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