Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of novel variants associated with osteoporosis, type 2 diabetes and potentially pleiotropic loci using pleiotropic cFDR method.

Bone - 1 Dec 2018

Hu Yuan, Tan Li-Jun, Chen Xiang-Ding, Greenbaum Jonathan, Deng Hong-Wen

Abstract excerpt

AIMS: Clinical and epidemiological findings point to an association between type 2 diabetes (T2D) and osteoporosis. Genome-wide association studies (GWASs) have been fruitful in identifying some loci potentially associated with osteoporosis and T2D respectively. However, the total genetic variance for each of these two diseases and the shared genetic determination between them are largely unknown. The aim of this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Density
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Femur Neck

Share to Gene Regulatory Networks

Share to Genetic Loci

Share to Genetic Pleiotropy

Share to Osteoporosis

Share to Physical Chromosome Mapping

Source

Open in PubMed Open full text

Identifiers

PMID: 30172742
DOI: 10.1016/j.bone.2018.08.020
PMCID: PMC6364698

Genes

PLEKHA1
CPE
GNG12
WLS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of novel variants associated with osteoporosis, type 2 diabetes and potentially pleiotropic loci using pleiotropic cFDR method.PMID 30172742Read ↗

Identification of Novel Potentially Pleiotropic Variants Associated With Osteoporosis and Obesity Using the cFDR Method.Semantic proximity Read ↗

Identifying potentially common genes between dyslipidemia and osteoporosis using novel analytical approaches.Semantic proximity Read ↗

Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.Semantic proximity Read ↗

Two novel pleiotropic loci associated with osteoporosis and abdominal obesity.Semantic proximity Read ↗

Pleiotropic genomic variants at 17q21.31 associated with bone mineral density and body fat mass: a bivariate genome-wide association analysis.Semantic proximity Read ↗

Enhanced Identification of Potential Pleiotropic Genetic Variants for Bone Mineral Density and Breast Cancer.Semantic proximity Read ↗

Identification of Novel Pleiotropic SNPs Associated with Osteoporosis and Rheumatoid Arthritis.Semantic proximity Read ↗

Increased detection of genetic loci associated with risk predictors of osteoporotic fracture using a pleiotropic cFDR method.Semantic proximity Read ↗

Identification of novel pleiotropic gene for bone mineral density and lean mass using the cFDR method.Semantic proximity Read ↗

Prediction of osteoporosis candidate genes by computational disease-gene identification strategy.Semantic proximity Read ↗

Bivariate genome-wide association analysis identified three pleiotropic loci underlying osteoporosis and obesity.Semantic proximity Read ↗

Identification of novel genetic loci for osteoporosis and/or rheumatoid arthritis using cFDR approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.