Article
Genetic Pleiotropy of Bone-Related Phenotypes: Insights from Osteoporosis.
Current osteoporosis reports - 1 Oct 2020
Christou M A, Ntzani E E, Karasik D
Abstract excerpt
PURPOSE OF REVIEW: We summarize recent evidence on the shared genetics within and outside the musculoskeletal system (mostly related to bone density and osteoporosis). RECENT FINDINGS: Osteoporosis is determined by an interplay between multiple genetic and environmental factors. Significant progress has been made regarding its genetic background revealing a number of robustly validated loci and respective...
Topics
- Bone Density
- Bone and Bones
- Gene-Environment Interaction
- Genetic Pleiotropy
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Osteoporosis
- Phenotype
