Article
Osteoporosis: A Silent Disease with Complex Genetic Contribution.
Journal of genetics and genomics = Yi chuan xue bao - 20 Feb 2016
Mafi Golchin Maryam, Heidari Laleh, Ghaderian Seyyed Mohammad Hossein, Akhavan-Niaki Haleh
Abstract excerpt
Osteoporosis is the most common multifactorial metabolic bone disorder worldwide with a strong genetic component. In this review, the evidence for a genetic contribution to osteoporosis and related phenotypes is summarized alongside with methods used to identify osteoporosis susceptibility genes. The key biological pathways involved in the skeleton and bone development are discussed with a particular focus on...
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