Article
Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jul 2010
Karasik David, Hsu Yi-Hsiang, Zhou Yanhua, Cupples L Adrienne, Kiel Douglas P, Demissie Serkalem
Abstract excerpt
Genome-wide association studies offer an unbiased approach to identify new candidate genes for osteoporosis. We examined the Affymetrix 500K + 50K SNP GeneChip marker sets for associations with multiple osteoporosis-related traits at various skeletal sites, including bone mineral density (BMD, hip and spine), heel ultrasound, and hip geometric indices in the Framingham Osteoporosis Study. We evaluated 433,510...
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