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Article

Using thermal scanning assays to test protein-protein interactions of inner-ear cadherins.

PloS one - 1 Jan 2017

Choudhary Deepanshu, Kumar Anusha, Magliery Thomas J, Sotomayor Marcos

Abstract excerpt

Protein-protein interactions play a crucial role in biological processes such as cell-cell adhesion, immune system-pathogen interactions, and sensory perception. Understanding the structural determinants of protein-protein complex formation and obtaining quantitative estimates of their dissociation constant (KD) are essential for the study of these interactions and for the discovery of new therapeutics. At the...

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Identifiers

PMID: 29261728
DOI: 10.1371/journal.pone.0189546
PMCID: PMC5736220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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