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Article

Optimal number of spacers in CRISPR arrays.

PLoS computational biology - 1 Dec 2017

Martynov Alexander, Severinov Konstantin, Ispolatov Iaroslav

Abstract excerpt

Prokaryotic organisms survive under constant pressure of viruses. CRISPR-Cas system provides its prokaryotic host with an adaptive immune defense against viruses that have been previously encountered. It consists of two components: Cas-proteins that cleave the foreign DNA and CRISPR array that suits as a virus recognition key. CRISPR array consists of a series of spacers, short pieces of DNA that originate from...

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Identifiers

PMID: 29253874
DOI: 10.1371/journal.pcbi.1005891
PMCID: PMC5749868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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