Article
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA.
Nature - 4 Nov 2010
Garneau Josiane E, Dupuis Marie-Ève, Villion Manuela, Romero Dennis A, Barrangou Rodolphe, Boyaval Patrick, Fremaux Christophe, Horvath Philippe, Magadán Alfonso H, Moineau Sylvain
Abstract excerpt
Bacteria and Archaea have developed several defence strategies against foreign nucleic acids such as viral genomes and plasmids. Among them, clustered regularly interspaced short palindromic repeats (CRISPR) loci together with cas (CRISPR-associated) genes form the CRISPR/Cas immune system, which...
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