Article
Maf1 phenotypes and cell physiology.
Biochimica et biophysica acta. Gene regulatory mechanisms - 1 Apr 2018
Willis Ian M
Abstract excerpt
As a master regulator of transcription by RNA polymerase (Pol) III, Maf1 represses the synthesis of highly abundant non-coding RNAs as anabolic signals dissipate, as the quality or quantity of nutrients decreases, and under a wide range of cellular and environmental stress conditions. Thus, Maf1 responds to changes in cell physiology to conserve metabolic energy and to help maintain appropriate levels of tRNAs...
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