Article
Maf1p, a negative effector of RNA polymerase III in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Aug 2001
Pluta K, Lefebvre O, Martin N C, Smagowicz W J, Stanford D R, Ellis S R, Hopper A K, Sentenac A, Boguta M
Abstract excerpt
Although yeast RNA polymerase III (Pol III) and the auxiliary factors TFIIIC and TFIIIB are well characterized, the mechanisms of class III gene regulation are poorly understood. Previous studies identified MAF1, a gene that affects tRNA suppressor efficiency and interacts genetically with Pol III. We show here that tRNA levels are elevated in maf1 mutant cells. In keeping with the higher levels of tRNA observed...
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