Article
Maf1, repressor of tRNA transcription, is involved in the control of gluconeogenetic genes in Saccharomyces cerevisiae.
Gene - 15 Aug 2013
Morawiec Ewa, Wichtowska Dominika, Graczyk Damian, Conesa Christine, Lefebvre Olivier, Boguta Magdalena
Abstract excerpt
Maf1 is a negative regulator of RNA polymerase III (Pol III) in yeast. Maf1-depleted cells manifest elevated tRNA transcription and inability to grow on non-fermentable carbon source, such as glycerol. Using genomic microarray approach, we examined the effect of Maf1 deletion on expression of Pol II-transcribed genes in yeast grown in medium containing glycerol. We found that transcription of FBP1 and PCK1, two...
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